當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 一抗 > bsm-62542RRho GTP酶激活蛋白26重組兔單抗
簡要描述:Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare gene
相關(guān)文章
Related Articles詳細介紹
產(chǎn)品咨詢